4+ day, 11+ hour ago   (187+ words) Background: Sarcopenia, characterised by reduced skeletal muscle mass, is increasingly recognised as a determinant of postoperative morbidity in patients with malignancy. Evidence regarding its association with short-term outcomes after liver resection for malignant tumours remains limited in Bangladesh. Objective: This…...

1+ week, 3+ day ago   (384+ words) Introduction Septic shock is a life-threatening condition with high mortality despite advances in critical care. Ferritin, an acute-phase reactant involved in iron metabolism and inflammation, along with its derived biomarkers, has emerged as a potential biomarker of disease severity in…...

1+ week, 3+ day ago   (273+ words) Periodontitis is a chronic inflammatory disease characterized by progressive destruction of the supporting structures of the teeth. While conventional therapies such as scaling and root planing (SRP) remain the cornerstone of treatment, their ability to restore previously lost periodontal attachment…...

1+ week, 3+ day ago   (340+ words) Background: Definitive radiotherapy represents a cornerstone treatment for localized prostate cancer, offering curative potential comparable to surgery. However, biochemical failure remains a concern, signaling possible disease progression. Objective: This study aimed to evaluate the frequency, timing, and predictors of biochemical…...

1+ week, 4+ day ago   (26+ words) Cureus Download Cureus Media Kit Public user content licensed CC-BY 4.0...

1+ week, 4+ day ago   (27+ words) Cureus Download Cureus Media Kit Public user content licensed CC-BY 4.0...

1+ week, 5+ day ago   (316+ words) Introduction: Acute appendicitis is a common pediatric emergency, but its severity is difficult to establish since conventional clinical, laboratory, and imaging methods are often imprecise, leading to unnecessary investigations or delayed care. Recent results suggest that basic inflammatory markers, especially…...

1+ week, 6+ day ago   (262+ words) Hemimandibulectomy may result in mandibular deviation toward the resected side due to loss of mandibular continuity and unopposed muscular forces, leading to impaired mastication, speech difficulties, and difficulty achieving functional occlusion. Conventional prosthodontic rehabilitation using guide flange and palatal ramp…...

1+ week, 6+ day ago   (209+ words) Cancer treatment is increasingly moving beyond single-agent strategies because tumor heterogeneity, clonal evolution, immune escape, and microenvironmental protection frequently limit durable disease control. Existing evidence remains fragmented across cancer types, treatment combinations, sequencing approaches, biomarker systems, and long-term safety outcomes,…...

1+ week, 6+ day ago   (201+ words) The Partner and Localizer of BRCA2 (PALB2) gene is a tumor suppressor gene with a role in DNA repair. Pathogenic autosomal dominant mutations of this gene significantly increase lifetime cancer risk, particularly breast and pancreatic cancers. We present a case of a…...